ncRNA name | ILAG siRNA |
ncRNA Category | siRNA |
Disease name | retinoblastoma (RB) |
Species | Homo sapiens |
Tissues/Cell_line | human RB cell lines Y79, Rb143 and Weri-Rb 27 |
Methods | siRNA transfection, Western blot, qPCR, immunocytochemistry, flow cytommetry, immunofluorescence |
Expression pattern | associated |
Functional description | Inhibition of ILK activity results in a concentration-dependent increase in nuclear area and multinucleated cells. Moreover, inhibition of ILK activity and expression increased the accumulation of multinucleated cells over time. |
PubMed ID | 24911651 |
Year | 2014 |
Title | Regulation of mitotic cytoskeleton dynamics and cytokinesis by integrin-linked kinase in retinoblastoma cells. |
Drug-related ncRNA | NO |
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