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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of retinoblastoma (RB)
ncRNA name ILAG siRNA
ncRNA Category siRNA
Disease name retinoblastoma (RB)
Species Homo sapiens
Tissues/Cell_line human RB cell lines Y79, Rb143 and Weri-Rb 27
Methods siRNA transfection, Western blot, qPCR, immunocytochemistry, flow cytommetry, immunofluorescence
Expression pattern associated
Functional description Inhibition of ILK activity results in a concentration-dependent increase in nuclear area and multinucleated cells. Moreover, inhibition of ILK activity and expression increased the accumulation of multinucleated cells over time.
PubMed ID 24911651
Year 2014
Title Regulation of mitotic cytoskeleton dynamics and cytokinesis by integrin-linked kinase in retinoblastoma cells.
Drug-related ncRNA NO

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